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drlowe.com
Homepage
Thyroid
Hormone Replacement Therapies:
Ineffective and Harmful for Many Hypothyroid Patients
May 4, 2004
Introduction
| Page1 | Page 2 |
Addenda | pdf
format
Clarifications | Selected Response
Letters
The document this page
introduces is a formal paper by Dr. John C. Lowe. In it, he presents documentary evidence for the ineffectiveness and
harm of
thyroid hormone replacement for
many hypothyroid patients.
The paper is a formal
critique of four studies published in 2003. These studies showed that two types of replacement therapies were
ineffective for many patients. Other studies, which
Dr. Lowe cites, also
show that patients using T4-replacement have an increased incidence
of other diseases associated with hypothyroidism, and increased
chronic use of drugs to control persisting hypothyroid symptoms and
the other diseases.
In that the paper is
a formal critique, Dr. Lowe had to present his arguments with
extreme precision. To do so required, at some points in the
paper, that he use language some patients with cognitive dysfunction
may find hard to understand. However, his Editor, Jackie Yellin,
worked with him to simplify the language as far as precision
allows. This makes most of the paper easy to understand.
If some parts of the paper aren't
clear to a reader, Dr. Lowe and Jackie encourage him or her to write for
clarification. (Please send emails to
DrJohnLowe@aol.com.)
The content of the paper is extremely important to the health and
well-being of hypothyroid patients. Because of that, we'll post
clarifications on a dedicated page at drlowe.com. We encourage
readers to bookmark the page and visit it at intervals to read the
clarifications.
Below is a
"Table of Contents" for the
paper. The Table contains links to different sections and subsections
of the paper.
This paper will soon
be published as an appendix in Dr. Lowe's new book titled Tyranny
of the TSH.
Full
Paper
pdf Version
|
Table of Contents
Section 1.
Abstract
Section 2. False Reports of 2003 Study Results and Potential Problems From Them
A. Valid and Invalid Conclusions of the Endocrinology Researchers, Commentators, and
Journalists
Section 3.
Endocrinologists’
Odd Treatment Advice for
Patients Who
Remain Symptomatic on T4-replacement Therapy
Section 4.
Alternate Approaches to Thyroid Hormone Therapy
A. Patient Safety
Section 5.
Potential Harm From TSH-Suppressive Dosages of Thyroid Hormone
A.
Central Limit Theorem and the Ineffectiveness and Dangers of Replacement Therapy for Many Patients
Section 6. Presumptions
of the Endocrinology Specialty: Instability of Desiccated Thyroid, Dangers of T3, and the
Safety and Effectiveness of T4-replacement
A.
Instability of Desiccated Thyroid
B. Dangers of T3
C.
Safety and Effectiveness of T4-replacement Therapy
(1) The Fraser Study
Section 7.
Consequences of the Presumption That T4-replacement is Invariably Safe
and Effective
A. Continued Suffering of Many Patients on
T4-replacement
b. Increased Incidence of Disease and
Medication Use Among Patients on T4-replacement
Section 8.
Dilemma for the
Endocrinology Specialty
References
Addendum 1. Inaccurate
Statements of the Endocrinology Researchers
Addendum 2. Endocrinologists’
Advice to Continue T4-replacement
Addendum 3. Persistent
Symptoms Among Patients Using Replacement Therapies
Addendum 4. Endocrinologists’
Warnings of Harm From
TSH-Suppressive Dosages of Thyroid Hormone
Addendum 5. About Dr. Hutton
Copyright
© John C. Lowe
Introduction
| Page1 | Page 2 |
Addenda | pdf
format
Clarifications | Selected Response Letters
|
