Thyroid Science, 4(3):CR1-3, 2009

Case Report: Hyperthyroidism,
Iron-deficiency Anemia, and Celiac Disease

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Cindy Huang, MD, PGY3¹
Amy Toscano-Zukor, DO²
Xiangbing Wang, MD, PhD<sup>2

1</sup>UMDNJ-Robert Wood Johnson Medical School, Department of Medicine,
One Robert Wood Johnson Place MEB 486, New Brunswick, NJ 08903-0019.

²UMDNJ-Robert Wood Johnson Medical School, Department of Endocrinology,
One Robert Wood Johnson Place MEB 384B, New Brunswick, NJ 08903-0019.

Contact: Dr. Cindy Huang, P: (908) 698-3988, F: (732) 422-1709, Cindy.Huang@gmail.com

ABSTRACT. The objective was to report a case of a woman with celiac disease presenting with hyperthyroidism and iron-deficiency anemia. Methods. We report the clinical course of this patient and her laboratory findings. We highlight the important associations between hyperthyroidism, iron-deficiency anemia, and celiac disease. The literature is reviewed for the typical and atypical presentations of celiac disease in relation to hyperthyroidism and iron-deficiency anemia. Results. A 37-year-old woman presented with symptoms of hyperthyroidism and was found to have iron-deficiency anemia. During the work up for iron-deficiency anemia, she was diagnosed with celiac disease on small-bowel biopsy. After being placed on a gluten-free diet, symptoms of hyperthyroidism improved without anti-thyroid medication. Conclusion. Our case demonstrates that routine screening for celiac disease should be highly considered for patients with both hyperthyroidism and iron-deficiency anemia. Treating celiac disease by gluten withdrawal may reduce morbidity and improve quality of life in patients with hyperthyroidism, anemia, and celiac disease.

Keywords. Celiac disease • Hyperthyroidism • Iron-deficiency anemia

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© 2009 Thyroid Science