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Thyroid Science 3(10):CLS1-6, 2008

Prevalence of Thyroid Dysfunction and
Its Effect on Serum Lipid Profiles in a
Murzok, Libya Population

(Full Text Free in pdf format)

Ali M. Nouh, Ibrahim A. M. Eshnaf, and Mohamed A. Basher

Sebha University Faculty of Engineering and Technology
Department of Medical Laboratory Sciences

Contact: Ali M. Nouh

ABSTRACT. The objective of this study was to assess the prevalence of thyroid dysfunction and its correlation with serum hyperlipidemia among the adult population of Murzok City, Libya. Blood samples were collected randomly from 356 subjects (179 male and 177 female) in the age range of 20-to-65 years. The blood was analyzed for the levels of total T3, total T4, free T4 and TSH by electrochemiluminescence immunoassay (ECLIA). Lipid levels of total cholesterol, triacylglycerol (TAG), LDL, and HDL were measured using the enzymatic colorimetric method.

The prevalence of thyroid dysfunction types was the following: overt hyperthyroidism (0.84%), subclinical hyperthyroidism (0.84%), overt hypothyroidism (1.12%), and subclinical hypothyroidism (6.18%). Also, thyroid dysfunction was more common in females (0.56%,
0.84%, 0.84%, and 4.21%) than in males (0.28%, 0.00%, 0.28%, and 1.97%).We found a higher prevalence of subclinical hypothyroidism (27%) among the subjects with hypercholesterolemia. We also found a significant negative correlation between subjects with normal T3 and hypercholesterolemia (P<0.05), and a significant positive correlation between subjects with 4 high T and HDL (P<0.05).

Keywords. Hypercholesterolemia Libya T3 T4 Thyroid dysfunction prevalence
Triacylglycerol TSH

Nouh, A.M., Ibrahim A. M. Eshnaf, I.A.M., and Basher, M.A.: Prevalence of thyroid dysfunction and its
effect on serum lipid profiles in a Murzok, Libya population. Thyroid Science, 3(10):CLS1-6, 2008.

(Full Text Free in pdf format)

2008 Thyroid Science